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PMID: 204 AngsutararuxPLuanpitpongSIssaragrisilS

In addition to neural connections, the central clock system also synchronizes the circadian rhythms of the peripheral clock system through hormones or factors, such as arginine vasopressin (AVP) and tumor necrosis factor (TNF) ( FIGURE 1 The clock system mainly regulates metabolism in the following three ways

Retinal microglial cells undergo P300-mediated lactylation of YY1, activating microglial cells by promoting the transcription of certain inflammatory genes [38]

Milk Thistle Extract and Alpha Lipoic Acid are included to enhance Glutathione's liver-supporting properties